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Zucapsaicin

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Drug Profile

Zucapsaicin

Alternative Names: cis-Capsaicin; Civamide; Civamide 0.075% cream - Winston Pharmaceuticals; Civanex; Civanex Nasal Solution; Dolorac Nasal Solution; Neuroderm Patch; Zuacta

Latest Information Update: 14 Apr 2021

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At a glance

  • Originator Winston Laboratories
  • Developer Sanofi; Winston Laboratories; Winston Pharmaceuticals
  • Class Catechols; Monounsaturated fatty acids; Polyunsaturated alkamides; Solanaceous alkaloids
  • Mechanism of Action TRPV1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Postherpetic neuralgia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Pain
  • Phase II Keratoconjunctivitis sicca
  • No development reported Cluster headache; Crohn's disease; Migraine; Postherpetic neuralgia; Rhinitis

Most Recent Events

  • 14 Apr 2021 Winston Laboratories plans a phase III trial in Cluster headache (Prevention, In adults, In the elderly) (Intranasal) in November 2021 (NCT01341548)
  • 13 Jul 2018 Valeant Pharmaceuticals International is now called Bausch Health Companies
  • 09 Jun 2015 No recent reports on development identified - Phase-II for Crohn's disease in USA (PO, capsule)

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