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Drug Profile


Alternative Names: Ezatiostat HCl; Ezatiostat hydrochloride; Telintra; TLK-199

Latest Information Update: 25 Aug 2015

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At a glance

  • Originator Telik
  • Developer MabVax Therapeutics; Telik
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Glutathione S-transferase pi inhibitors; JNK mitogen-activated protein kinase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myelodysplastic syndromes
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Myelodysplastic syndromes; Neutropenia

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 25 Aug 2015 No recent reports of development identified - Phase-I for Myelodysplastic syndromes (Combination therapy) in USA (PO)
  • 25 Aug 2015 No recent reports of development identified - Phase-II for Myelodysplastic syndromes (Monotherapy) in USA (PO)
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