Rifaximin - Alfa Wassermann

Drug Profile

Rifaximin - Alfa Wassermann

Alternative Names: Dermodis; EIR formulation of rifaximin - Salix Pharmaceuticals; Flonorm; L-105; Lumenax; Normix; RedActive®; Rifacol; Rifaxidin®; Rifaximin soluble solid dispersion tablet; Rifaximin SSD/next generation formulation; Rifaximin-a 550mg; rifaximin-alpha; Rifxima; Spiraxin; Targaxan 550; Tixtar; Xifaxan; Xifaxan 550mg; XIFAXAN550; Xifaxanta; Zaxine

Latest Information Update: 20 Sep 2018

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At a glance

  • Originator Alfa Wassermann SpA
  • Developer Alfa Wassermann SpA; ASKA Pharmaceutical; Lupin; Norgine; Salix Pharmaceuticals
  • Class Antibacterials; Antidiarrhoeals; Hepatoprotectants; Irritable bowel syndrome therapies; Rifamycins; Small molecules
  • Mechanism of Action DNA-directed RNA polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hepatic encephalopathy
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Diverticulitis; Hepatic encephalopathy; Hyperammonaemia; Intestinal infections; Irritable bowel syndrome; Skin and soft tissue infections; Traveller's diarrhoea
  • Phase III Crohn's disease
  • Phase II Liver disorders
  • Discontinued Bacterial vaginosis; Clostridium-difficile-infections; Pouchitis; Shigella infections

Most Recent Events

  • 12 Sep 2018 Bausch Health Companies, Salix Pharmaceuticals, Cedars-Sinai Medical Center and Alfasigma agree to grant a non-exclusive license to rifaximin 550mg tablet to Actavis Laboratories in USA
  • 12 Sep 2018 Bausch Health Companies, Salix Pharmaceuticals, Cedars-Sinai Medical Center and Alfasigma will grant a non-exclusive license to rifaximin 550mg tablet to Actavis Laboratories in USA, effective January 2028
  • 12 Sep 2018 Bausch Health Companies, Salix Pharmaceuticals, Cedars-Sinai Medical Center and Alfasigma agree to resolve the outstanding intellectual property litigation with Actavis Laboratories relating to rifaximin (XIFAXAN®) 550mg tablet
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