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Pregabalin - Pfizer

Drug Profile

Pregabalin - Pfizer

Alternative Names: CI 1008; Isobutylgaba; Lyrica; PD 144723

Latest Information Update: 03 Dec 2018

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At a glance

  • Originator Northwestern University
  • Developer Eisai Co Ltd; Pfizer
  • Class Aminobutyric acids; Analgesics; Antiepileptic drugs; Anxiolytics; Neuroprotectants; Small molecules
  • Mechanism of Action CACNA2D1 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Fibromyalgia; Generalised anxiety disorder; Neuropathic pain; Partial epilepsies; Postherpetic neuralgia
  • Phase III Tonic-clonic epilepsy
  • Discontinued Pain; Postoperative pain; Restless legs syndrome

Most Recent Events

  • 27 Nov 2018 The USFDA grants six months pediatric exclusivity for Pregabalin
  • 12 Sep 2018 Efficacy and adverse events data from a phase III trial in Peripheral neuropathic pain (Post-traumatic) presented at the 17th World Congress on Pain (WCP-2018)
  • 01 Jul 2018 Pfizer completes a phase II trial in Neuropathic pain in USA (PO) (NCT02607254)
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