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Drug Profile


Alternative Names: Interleukin-4 - DNAX; Quadrakine; SCH 39400

Latest Information Update: 20 Aug 2009

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At a glance

  • Originator Schering-Plough
  • Developer Nonindustrial sources; Schering-Plough
  • Class Interleukins
  • Mechanism of Action B cell stimulants; Interleukin 1 beta inhibitors; Interleukin 4 receptor agonists; Interleukin 6 receptor antagonists; Interleukin 8 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Gastrointestinal cancer; Immunodeficiency disorders; Inflammation; Kaposi's sarcoma; Malignant melanoma; Non-small cell lung cancer; Precursor cell lymphoblastic leukaemia-lymphoma; Psoriasis; Rheumatoid arthritis; Solid tumours

Most Recent Events

  • 20 Aug 2009 Discontinued - Clinical-Phase-Unknown for Psoriasis in Netherlands (SC)
  • 26 May 2003 Clinical trials in Psoriasis in Germany (SC)
  • 26 May 2003 Clinical trials in Psoriasis in Netherlands (SC)
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