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Drug Profile


Alternative Names: Flurbinitroxybutylester; Flurbiprofen nitroxybutylester; HCT 1026; NO-flurbiprofen

Latest Information Update: 16 Sep 2009

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At a glance

  • Originator NicOx
  • Class Antidementias; Neuroprotectants; Nonsteroidal anti-inflammatories; Propionic acids; Small molecules
  • Mechanism of Action Cyclooxygenase inhibitors; Nitric oxide donors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alzheimer's disease; Coronary artery restenosis; Inflammation; Osteitis deformans; Overactive bladder; Postmenopausal osteoporosis; Skin disorders; Urinary incontinence; Urticaria

Most Recent Events

  • 03 Nov 2006 Data presented at the 36th Annual Meeting of the Society for Neuroscience (SfN-2006) have been added to the Parkinson's disease pharmacodynamics section
  • 24 Mar 2006 No development reported - Phase-II for Osteitis deformans in United Kingdom (PO)
  • 24 Mar 2006 No development reported - Phase-II for Overactive bladder in France (PO)
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