Posaconazole - Merck & Co.

Drug Profile

Posaconazole - Merck & Co.

Alternative Names: IV posaconazole; MK-5592; Noxafil; Posaconazole oral suspension; Posaconazole SP; Posaconazole tablet; Posanol; SCH 056592; SCH 56592; Spriafil

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Schering-Plough
  • Developer Merck & Co; MSD China; Schering-Plough
  • Class Antifungals; Triazoles
  • Mechanism of Action 14-alpha demethylase inhibitors; Cytochrome P 450 enzyme system inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Aspergillosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Aspergillosis; Candidiasis; Mycoses; Oropharyngeal candidiasis
  • Phase II Chagas disease

Most Recent Events

  • 24 Jan 2018 Merck completes a phase III trial in Aspergillosis in Japan (IV) (NCT02180165)
  • 20 Dec 2017 Phase-I clinical trials in Mycoses (Prevention) in China (IV) (NCT03336502)
  • 20 Dec 2017 Merck initiates enrolment in a phase I trial in Mycoses (Prevention) in China (PO, Suspension) (NCT03336502)
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