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Somatropin - Merck Serono

Drug Profile

Somatropin - Merck Serono

Alternative Names: r-hGH; Saizen; Serostim; SJ 0011; Zorbtive

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Merck Serono
  • Developer Bioject; Merck Serono; Savient Pharmaceuticals
  • Class Growth hormones; Hormonal replacements; Obesity therapies
  • Mechanism of Action Intercellular signalling peptide and protein stimulants; Somatotropin receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cachexia; Short bowel syndrome; Lipodystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cachexia; Growth disorders; Short bowel syndrome; Short stature; Somatotropin deficiency
  • Phase III Female infertility
  • Discontinued Lipodystrophy

Most Recent Events

  • 08 May 2015 AEterna Zentaris and ASCEND therapeutics agree to promote somatropin in USA
  • 01 May 2015 EMD Serono completes a phase II trial in Female infertility (Adjunctive treatment) in Canada (NCT01204840)
  • 14 Oct 2013 Savient Pharmaceuticals files for Chapter 11 bankruptcy
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