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At a glance
Originator
Roche
Developer
Alliance for Clinical Trials in Oncology; Beth Israel Deaconess Medical Center; Chugai Pharmaceutical; Dana-Farber Cancer Institute; Ludwig-Maximilians-University; Roche; Samsung Medical Center; Sanofi; University of Chicago
Class
Antineoplastics; Carbamates; Pyrimidine nucleosides; Small molecules
Mechanism of Action
Thymidylate synthase inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
No
New Molecular Entity
Yes
Highest Development Phases
Marketed
Breast cancer; Colorectal cancer; Gastric cancer
Registered
Pancreatic cancer; Rectal cancer
Phase II
Glioma; Intestinal cancer; Oesophageal cancer
No development reported
Cervical cancer
Discontinued
Biliary cancer; Lung cancer; Nasopharyngeal cancer
Most Recent Events
28 Jun 2023
Efficacy data from a phase III trial in Colorectal Cancer presented at the 25th World Congress on Gastrointestinal Cancer (WCGC-2023)
27 Apr 2023
Chugai Pharmaceuticals submits company opinion for capecitabine for Neuroendocrine tumors to MHLW review comittee (Chugai Pharmaceuticals pipeline, May 2023)
24 Jan 2023
CHEPLAPHARM acquires capecitabin (Xeloda®) from Roche
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