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Capecitabine - Roche

Drug Profile

Capecitabine - Roche

Alternative Names: Capecitabine RDT; R340; RG 340; RO 091978; Ro09-1978; Xeloda; Xelox

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Roche
  • Developer Alliance for Clinical Trials in Oncology; Beth Israel Deaconess Medical Center; Chugai Pharmaceutical; Dana-Farber Cancer Institute; Ludwig-Maximilians-University; Roche; Samsung Medical Center; Sanofi; University of Chicago
  • Class Antineoplastics; Carbamates; Pyrimidine nucleosides; Small molecules
  • Mechanism of Action Thymidylate synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer; Colorectal cancer; Gastric cancer
  • Registered Pancreatic cancer; Rectal cancer
  • Phase II Glioma; Intestinal cancer; Oesophageal cancer
  • No development reported Cervical cancer; Lung cancer; Nasopharyngeal cancer
  • Discontinued Biliary cancer

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 01 Sep 2017 Yakult Honsha initiates enrolment in a phase II trial in Gastric cancer (Combination therapy, Late-stage disease, Metastatic disease) in Japan (IV) (UMIN000028749)
  • 01 Apr 2017 Roche terminates a phase III trial in Colorectal cancer (First-line therapy, Metastatic disease) in South Korea (PO) (NCT02060669)
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