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Ibritumomab tiuxetan - Acrotech Biopharma /Biogen

Drug Profile

Ibritumomab tiuxetan - Acrotech Biopharma /Biogen

Alternative Names: 111In-ibritumomab tiuxetan; BAY86-5128; IDEC-129; IDEC-In2B8; IDEC-Y2B8; Indium-111 Ibritumomab tiuxetan; Monoclonal antibody IDEC-Y2B8; SH-L-749; Yttrium-90 ibritumomab tiuxetan; ZEVALIN; Zevalin; Zevamab

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Biogen Idec
  • Developer Acrotech Biopharma; Bayer Yakuhin; Biogen; CASI Pharmaceuticals; Dana-Farber Cancer Institute; Schering Korea; Tufts-New England Medical Center
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies; Radioisotopes; Radiopharmaceutical diagnostics; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Non-Hodgkin's lymphoma
  • Discontinued Diffuse large B cell lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Multiple myeloma

Most Recent Events

  • 16 Mar 2020 CASI Pharmaceuticals plans registration trial for Non-Hodgkin's lymphoma in China in early 2021
  • 06 Mar 2019 Spectrum Pharmaceuticals completes sale of ibritumomab tiuxetan to Acrotech Biopharma
  • 19 Feb 2019 The National Medical Products Administration (NMPA) of China approves a clinical trial application for the conduction of a confirmatory clinical trial of ibritumomab tiuxetan in Non-Hodgkin's lymphoma (Second-line therapy or greater)
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