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Ibritumomab tiuxetan - Spectrum Pharmaceuticals/Biogen

Drug Profile

Ibritumomab tiuxetan - Spectrum Pharmaceuticals/Biogen

Alternative Names: 111In-ibritumomab tiuxetan; BAY86-5128; IDEC-129; IDEC-In2B8; IDEC-Y2B8; Indium-111 Ibritumomab tiuxetan; Monoclonal antibody IDEC-Y2B8; SH-L-749; Yttrium-90 ibritumomab tiuxetan; ZEVALIN; Zevalin; Zevamab

Latest Information Update: 21 Feb 2019

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At a glance

  • Originator Biogen Idec
  • Developer Bayer Yakuhin; Biogen; CASI Pharmaceuticals; Dana-Farber Cancer Institute; Schering Korea; Spectrum Pharmaceuticals; Tufts-New England Medical Center
  • Class Antineoplastics; Immunoconjugates; Monoclonal antibodies; Radioisotopes; Radiopharmaceutical diagnostics; Radiopharmaceuticals
  • Mechanism of Action CD20 antigen inhibitors; Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Non-Hodgkin's lymphoma
  • Discontinued Diffuse large B cell lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Multiple myeloma

Most Recent Events

  • 19 Feb 2019 The National Medical Products Administration (NMPA) of China approves a clinical trial application for the conduction of a confirmatory clinical trial of ibritumomab tiuxetan in Non-Hodgkin's lymphoma (Second-line therapy or greater)
  • 11 Sep 2018 Product re-launched for indolent Non-Hodgkin's lymphoma (Combination therapy, Second-line therapy or greater) during before September 2018 in Canada
  • 24 Jun 2018 Biomarkers information updated
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