AG 490

Drug Profile

AG 490

Alternative Names: AG-490

Latest Information Update: 28 Feb 2008

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At a glance

  • Originator Hebrew University of Jerusalem; The Hospital for Sick Children; University of Toronto
  • Developer Friedrich-Alexander-University Erlangen-Nuremberg; Hebrew University of Jerusalem; The Hospital for Sick Children; University of Toronto; Yissum Research Development Company
  • Class Antineoplastics; Tyrphostins
  • Mechanism of Action Janus kinase-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Multiple myeloma; Precursor cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 06 Apr 2000 Pharmacia & Upjohn has merged with Monsanto to form Pharmacia Corporation
  • 21 Sep 1999 SUGEN has been acquired by Pharmacia & Upjohn
  • 20 Aug 1998 Preclinical development for Multiple myeloma in Germany (Unknown route)
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