Levofolinic acid

Drug Profile

Levofolinic acid

Alternative Names: Calcium levofolinate; Calcium levoleucovorin; FUSILEV; Isovorin; Levofolinate; Levofolinate calcium; Levoleucovorin; Levoleucovorin calcium pentahydrate

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Wyeth
  • Developer Spectrum Pharmaceuticals
  • Class Antidotes; Antineoplastics; Formyltetrahydrofolates; Small molecules
  • Mechanism of Action
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Colorectal cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Anaemia; Colorectal cancer; Osteosarcoma

Most Recent Events

  • 27 Oct 2016 Chemical structure information added
  • 27 Oct 2015 First generic equivalent available in USA for Osteosarcoma
  • 13 Jul 2013 Spectrum Pharmaceuticals withdraws a phase I trial prior to enrolment for Stomatitis (prevention and reduction) in patients with non-Hodgkin's lymphoma in USA (NCT01789723)
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