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Sildenafil - Pfizer

Drug Profile

Sildenafil - Pfizer

Alternative Names: Revatio; Revatio IV; Sildenafil citrate; UK 92480; Viagra

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Pfizer
  • Developer Pfizer; University of Calgary
  • Class Antihypertensives; Erectile dysfunction therapies; Phenyl ethers; Piperazines; Purines; Pyrazoles; Pyrimidinones; Small molecules; Sulfonamides
  • Mechanism of Action Type 5 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension; Heart failure; Pulmonary hypertension
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Erectile dysfunction; Pulmonary arterial hypertension
  • Phase III Heart failure; Pulmonary hypertension
  • No development reported Female infertility; Raynaud's disease
  • Discontinued Angina pectoris; Cardiovascular disorders; Eye disorders; Female sexual dysfunction; Meniere's disease

Most Recent Events

  • 12 Mar 2018 Pfizer completes a phase III trial for Pulmonary arterial hypertension (In infants, In children, In adolescents) in Japan (PO) (NCT01642407)
  • 12 Mar 2018 Phase-III clinical trials in Heart failure (Prevention) in Canada (PO) (NCT03356353)
  • 04 Nov 2017 No recent reports of development identified for clinical-Phase-Unknown development in Female-infertility in USA (Vaginal)
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