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Leukocyte interleukin - CEL-SCI

Drug Profile

Leukocyte interleukin - CEL-SCI

Alternative Names: BC-IL; Buffy coat interleukins - CEL-SCI; Interleukin-2 cocktail - CEL-SCI; Leucocyte Interleukin injection - CEL-SCI; Multikine

Latest Information Update: 21 May 2019

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At a glance

  • Originator CEL-SCI Corporation
  • Developer CEL-SCI Corporation; Ergomed; Naval Medical Research Center; Orient Europharma; Teva Pharmaceutical Industries
  • Class Antineoplastics; Granulocyte-macrophage colony-stimulating factors; Interferons; Interleukins
  • Mechanism of Action Immunostimulants; Natural killer cell stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Head and neck cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Head and neck cancer
  • No development reported Cervical dysplasia; Condylomata acuminata
  • Discontinued Breast cancer; HIV infections; Prostate cancer

Most Recent Events

  • 29 Mar 2019 An Independent Data Monitoring Committee recommends continuation of a phase III trial in Head and neck cancer
  • 08 Dec 2017 CEL-SCI completes the phase III IT-MATTERS trial in Head and neck cancer (First-line therapy, Neoadjuvant therapy) in in USA, Poland, India, Poland, Canada, Israel, Russia, Taiwan, Croatia, Hungary, Bosnia-Herzegovina, Serbia, Ukraine, Austria, United Kingdom, France, Sri Lanka, Turkey, Thailand, Italy, Spain, Malaysia, Romania, Belarus (Perilesional) (NCT01265849)
  • 07 Dec 2017 An Independent Data Monitoring Committee recommends continuation of a phase III trial in Head and neck cancer
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