Natalizumab - Biogen/Perrigo
Alternative Names: AN 10022; AN 100226; Antegren; Anti-alpha4 integrin monoclonal antibody - Biogen/Perrigo; BG-00002; BG-0002; BG-0002-E; TysabriLatest Information Update: 26 Nov 2024
Price :
$50 *
At a glance
- Originator Elan Corporation
- Developer Biogen; Biogen Idec; Elan Corporation; Perrigo
- Class Anti-inflammatories; Antiepileptic drugs; Antineoplastics; Antirheumatics; Immunotherapies; Monoclonal antibodies; Vascular disorder therapies
- Mechanism of Action Integrin alpha4beta1 antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Crohn's disease; Multiple sclerosis
- Phase II Graft-versus-host disease
- Discontinued Epilepsy; Multiple myeloma; Rheumatoid arthritis; Stroke
Most Recent Events
- 26 Nov 2024 No development reported - Preregistration for Multiple sclerosis in USA (SC) (Biogen pipeline, November 2024)
- 27 May 2024 Biogen terminates a Phase-III clinical trials in Multiple sclerosis in Japan (SC) due to sponsors decision (NCT05265728)
- 11 Oct 2023 Adverse events data from the phase III NOVA trial in Multiple sclerosis were presented at the 9th Triennial joint meeting of Americas Committee for Treatment and Research in Multiple Sclerosis and the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS-ACTRIMS)