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Celecoxib - Pfizer/Astellas Pharma

Drug Profile

Celecoxib - Pfizer/Astellas Pharma

Alternative Names: Celebra; Celebrex; Celecox; Niflam; Onsenal; SC-58635; YM-177

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Pfizer
  • Developer Astellas Pharma; Dana-Farber Cancer Institute; Department of Veterans Affairs; Linkoping University Hospital; Pfizer; Swedish Lung Cancer Study Group; University of Connecticut; Zydus Cadila
  • Class Antirheumatics; Non-opioid analgesics; Nonsteroidal anti-inflammatories; Pyrazoles; Small molecules; Sulfonamides
  • Mechanism of Action Cyclo-oxygenase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Familial adenomatous polyposis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute pain; Ankylosing spondylitis; Back pain; Cervicobrachial syndrome; Dental pain; Dysmenorrhoea; Familial adenomatous polyposis; Juvenile rheumatoid arthritis; Osteoarthritis; Pain; Periarthritis; Postoperative pain; Rheumatic disorders; Rheumatoid arthritis; Tendinitis; Tenosynovitis
  • Phase III Non-small cell lung cancer
  • Phase II Stomatitis
  • Discontinued Alzheimer's disease; Bladder cancer; Gouty arthritis; Prostate cancer

Most Recent Events

  • 01 Feb 2017 Pfizer terminates a phase I trial in Uveitis (In adolescents, In adults, In the elderly) due to difficulty in recruitment in USA (NCT02131012)
  • 13 Nov 2016 Top-line efficacy data from the phase IV PRECISION trial in Rheumatic arthritis released by Pfizer
  • 15 Mar 2016 Biomarkers information updated
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