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T cell replacement therapy - Kiadis Pharma

Drug Profile

T cell replacement therapy - Kiadis Pharma

Alternative Names: ATIR; ATIR-101; ATIR-201; ATIR101; Reviroc™; Rhitol™; T cell replacement therapy TH9402

Latest Information Update: 16 Oct 2018

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At a glance

  • Originator University of Montreal
  • Developer Kiadis Pharma
  • Class Immunotherapies; Stem cell therapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia; Bone marrow transplant rejection; Transplant rejection; Follicular lymphoma; Graft-versus-host disease; B-cell lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Preregistration Graft-versus-host disease
  • Phase III Acute myeloid leukaemia
  • Phase II Bone marrow transplant rejection; Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase I/II Beta-thalassaemia
  • Discontinued Chronic myeloid leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 12 Oct 2018 Kiadis Pharma expects to receive a Committee for Medicinal Products for Human Use opinion for Graft-versus-host disease (Adjunctive treatment, Prevention) in H1 2019
  • 31 Aug 2018 Pooled efficacy data from two phase II trials in Graft versus host disease released by Kiadis Pharma
  • 28 Aug 2018 Kiadis Pharma announces intention to file BLA to the US FDA for Graft-versus-host disease
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