T cell replacement therapy - Kiadis Pharma

Drug Profile

T cell replacement therapy - Kiadis Pharma

Alternative Names: Allodepleted T-cell ImmunotheRapeutics; ATIR; ATIR-101; ATIR-201; ATIR101; Reviroc™; Rhitol™; T cell replacement therapy TH9402; TH-9402

Latest Information Update: 16 Mar 2018

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At a glance

  • Originator University of Montreal
  • Developer Kiadis Pharma
  • Class T lymphocyte cell therapies
  • Mechanism of Action Immunostimulants; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia; Bone marrow transplant rejection; Transplant rejection; Follicular lymphoma; Graft-versus-host disease; B cell lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Preregistration Graft-versus-host disease
  • Phase III Acute myeloid leukaemia
  • Phase II Bone marrow transplant rejection; Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase I/II Beta-thalassaemia
  • Discontinued Chronic myeloid leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 12 Mar 2018 Kiadis Pharma plans a clinical trial for Graft-versus-host disease in conjunction with another T-cell depleted haematopoietic stem cell transplantation (HSCT) protocol or with a cyclophosphamide-based haplo transplantation protocol
  • 31 Jan 2018 Kiadis Pharma completes enrolment in the phase II trial in Graft-versus-host disease (Adjunctive treatment, Prevention) in Belgium, Canada, Germany, United Kingdom, Croatia and Portugal
  • 10 Oct 2017 Kiadis Pharma plans a clinical trial for Graft-versus-host disease (Prevention, Combination therapy)
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