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PEGylated haemoglobin and carbon monoxide - Prolong Pharmaceuticals

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Drug Profile

PEGylated haemoglobin and carbon monoxide - Prolong Pharmaceuticals

Alternative Names: PEG haemoglobin; PEG haemoglobin carbon monoxide; PEG-bHb-CO; PEG-COHb; PEG-haemoglobin-CO; PEG-Hb; PEG-LEH; Pegylated carboxyhemoglobin bovine; Pegylated haemoglobin carbon monoxide; Polyethylene glycol modified bovine haemoglobin; PP-007 - Prolong Pharmaceuticals; Sanguinate

Latest Information Update: 11 Feb 2025

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At a glance

  • Originator Enzon Pharmaceuticals; Rutgers
  • Developer Prolong Pharmaceuticals
  • Class Anti-ischaemics; Antifibrotics; Haemoglobins; Polyethylene glycols; Recombinant proteins; Vascular disorder therapies
  • Mechanism of Action Oxygen carriers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Delayed graft function
  • Phase II Cerebral ischaemia; Leg ulcer; Vaso-occlusive crisis
  • Phase I Ischaemic stroke
  • Preclinical Cystic fibrosis; Haemorrhagic shock
  • No development reported Beta-thalassaemia

Most Recent Events

  • 05 Feb 2025 Phase I development in Ischaemic stroke is still ongoing in USA (IV, Infusion) (NCT04677777)
  • 05 Feb 2025 Prolong Pharmaceuticals plans the phase III HEMERA-2 trial for Ischaemic stroke
  • 28 Nov 2024 No recent reports of development identified for phase-I development in Stroke in USA (IV, Infusion)

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