Gelsolin - BioAegis Therapeutics

Drug Profile

Gelsolin - BioAegis Therapeutics

Alternative Names: Gelsolin recombinant; hu r-P gelsolin; pGSN; Recombinant human plasma gelsolin; rh gelsolin; rhu-pGSN; Solinex

Latest Information Update: 10 Sep 2018

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At a glance

  • Originator Brigham and Womens Hospital
  • Developer BioAegis Therapeutics; Critical Biologics Corporation
  • Class Anti-inflammatories; Antibacterials; Antifibrotics; Antineoplastics; Bronchodilators; Expectorants; Proteins
  • Mechanism of Action Actin inhibitors; Protein replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Community-acquired pneumonia
  • Discontinued Bronchitis; Cystic fibrosis; Systemic inflammatory response syndrome

Most Recent Events

  • 03 Aug 2018 Phase-I/II clinical trials in Community-acquired pneumonia in Australia (IV) (NCT03466073)
  • 24 Jun 2018 Biomarkers information updated
  • 04 Oct 2017 Preclinical pharmacodynamics data in Pneumonia presented at the IDWeek 2017 (IDW-2017)
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