Ajulemic acid - Corbus Pharmaceuticals

Drug Profile

Ajulemic acid - Corbus Pharmaceuticals

Alternative Names: Anabasum; CPL-7075; CT-3; DMH-11C; HU-239; IP-751; JBT-101; Lenabasum; Resunab

Latest Information Update: 19 Mar 2018

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At a glance

  • Originator University of Massachusetts Medical School
  • Developer Cervelo Pharmaceuticals; Corbus Pharmaceuticals; Indevus Pharmaceuticals; National Institute of Arthritis and Musculoskeletal and Skin Diseases; University of Erlangen-Nuremberg; University of Pennsylvania; University of Siena
  • Class Anti-inflammatories; Antiasthmatics; Antifibrotics; Antirheumatics; Cannabinoids; Non-opioid analgesics; Small molecules
  • Mechanism of Action Cannabinoid receptor CB2 agonists; Lipoxygenase-cyclooxygenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis; Systemic scleroderma
  • New Molecular Entity Yes
  • Available For Licensing Yes - Interstitial cystitis

Highest Development Phases

  • Phase III Systemic scleroderma
  • Phase II Cystic fibrosis; Dermatomyositis; Systemic lupus erythematosus
  • Phase I Inflammation
  • Preclinical Pulmonary fibrosis
  • Discontinued Interstitial cystitis; Muscle spasticity; Neuropathic pain; Pain; Poisoning

Most Recent Events

  • 07 Feb 2018 Phase-II clinical trials in Cystic fibrosis (In children, In adults, In adolescents) in USA (NCT03451045)
  • 06 Feb 2018 Corbus plans a phase III trial for Dermatomyositis in second half of 2018
  • 30 Jan 2018 Corbus Pharmaceuticals plans a phase IIb trial for Cystic fibrosis (In children, In adolescents, In adults) in North America, Europe, Israel and Australia in the first quarter of 2018
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