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Ibutamoren - Lumos Pharma/Merck

Drug Profile

Ibutamoren - Lumos Pharma/Merck

Alternative Names: Ibutamoren mesilate; Ibutamoren mesylate; L 163191; LUM-201; MK-0677; MK-677; Oratrope

Latest Information Update: 11 Jun 2024

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At a glance

  • Originator Merck & Co
  • Developer Lumos Pharma; Massachusetts General Hospital; Merck & Co
  • Class Antidementias; Hepatoprotectants; Indoles; Osteoporosis therapies; Small molecules; Spiro compounds
  • Mechanism of Action Growth hormone releasing factor agonists; Insulin-like growth factor I stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Somatotropin deficiency
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Non-alcoholic fatty liver disease; Somatotropin deficiency
  • Phase I Turner's syndrome
  • Discontinued Alzheimer's disease; Fibromyalgia; Fracture; Postmenopausal osteoporosis; Sarcopenia

Most Recent Events

  • 05 Jun 2024 Updated efficacy data from a phase II OraGrowtH212 trial in Somatotropin deficiency released by Lumos Pharma
  • 12 Apr 2024 Lumos Pharma has patent protection for Ibutamoren in Canada before April 2024 (Lumos Pharma, Form 10-K)
  • 12 Apr 2024 Lumos Pharma has patent protection for method of use of Ibutamoren for growth hormone deficiency disorders in USA before April 2024 (Lumos Pharma, Form 10-K)
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