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Drug Profile


Alternative Names: Ibutamoren mesilate; Ibutamoren mesylate; L 163191; MK-0677; MK-677; Oratrope™

Latest Information Update: 18 May 2018

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At a glance

  • Originator Merck & Co
  • Developer Ammonett Pharma; Merck & Co
  • Class Indoles; Small molecules; Spiro compounds
  • Mechanism of Action Growth hormone releasing factor agonists; Insulin-like growth factor I stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Somatotropin deficiency
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Somatotropin deficiency
  • No development reported Fibromyalgia; Muscular atrophy
  • Discontinued Alzheimer's disease; Fracture; Postmenopausal osteoporosis

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 19 Jun 2017 Ibutamoren receives Orphan Drug status for Somatotropin deficiency (In children) in USA
  • 25 May 2017 Ammonett Pharma receives Notice of allowance for ibutamoren in USA
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