Drug Profile

Efalizumab -Genentech/XOMA

Alternative Names: Anti-CD11a monoclonal antibody - Genentech/Xoma; HU 1124; Hu1124; Raptiva; Xanelim™

Latest Information Update: 17 Jul 2026

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At a glance

Originator Genentech
Developer Genentech; Merck Serono; XOMA
Class Monoclonal antibodies
Mechanism of Action CD11a antigen antagonists; Immunosuppressants; T cell activation inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Marketed Psoriasis
Discontinued Psoriatic arthritis; Type 1 diabetes mellitus

Most Recent Events

14 Jul 2026 XOMA has been acquired by Ligand Pharmaceuticals
11 Jun 2009 Withdrawn for Psoriasis in Canada (SC)
08 Jun 2009 Withdrawn for Psoriasis in European Union (SC)

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