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At a glance
Originator
Columbia University; Memorial Sloan-Kettering Cancer Center
Developer
Banyu; Bayer; Columbia University; Dana-Farber Cancer Institute; Fred Hutchinson Cancer Research Center; Groupe Francophone des Myelodysplasies; H. Lee Moffitt Cancer Center and Research Institute; Indiana University; Massachusetts General Hospital; Memorial Sloan-Kettering Cancer Center; Merck & Co; National Center for Tumor Diseases; Roswell Park Cancer Institute; Stanford University; Takeda; University Hospital Heidelberg; University of North Carolina at Chapel Hill; University of Texas M. D. Anderson Cancer Center
Class
Antineoplastics; Hydroxamic acids; Small molecules
Mechanism of Action
Histone deacetylase inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
29 May 2020
Efficacy and adverse events data from a phase I/II trial in Non small cell lung cancer presented at the 56th Annual Meeting of the American Society of Clinical Oncology (ASCO-2020)
09 Apr 2019
Merck & Co and the Peter Doherty Institute for Infection and Immunity terminates the phase I/II DIVA trial in HIV-1 infections in Australia due to greater risk was involved in evaluation of the hypothesis in the patients than originally anticipated (NCT03198559)
08 Feb 2019
Merck & Co completes a phase II trial in B-cell lymphoma in South-East Asia (PO) (NCT00875056)
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