Rilimogene galvacirepvec-rilimogene glafolivec - BN ImmunoTherapeutics

Drug Profile

Rilimogene galvacirepvec-rilimogene glafolivec - BN ImmunoTherapeutics

Alternative Names: PROSTVAC; PROSTVAC-V-PROSTVAC-F; PROSTVAC-VF-TRICOM; PSA-TRICOM; Rilimogene gamvacirepvec-rilimogene glafolivec; Rilimogene-glafolivec-rilimogene-galvacirepvec; Vaccinia PSA TRICOM-fowlpox PSA TRICOM

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator National Cancer Institute (USA)
  • Developer BN ImmunoTherapeutics; National Cancer Institute (USA); University of California at San Francisco
  • Class Antineoplastics; Cancer vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Prostate cancer

Most Recent Events

  • 20 Oct 2017 National Cancer Institute plans a phase II trial of the combination of rilimogene galvacirepvec-rilimogene glafolivec, CV 301 and MSB 0011359C for Prostate cancer (Combination therapy) in USA (NCT03315871)
  • 14 Sep 2017 Bavarian Nordic terminates the phase III PROSPECT trial for Prostate cancer in USA, Australia, Belgium, Canada, Denmark, Estonia, France, Germany, Iceland, Israel, Poland, Puerto Rico, Russia, Spain, the Netherlands and United Kingdom as per the independent Data Monitoring Committee recommendation (NCT01322490)
  • 14 Sep 2017 An independent Data Monitoring Committee recommends discontinuation of the phase III PROSPECT trial in Prostate cancer based on a preplanned interim analysis
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