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Pretomanid - Global Alliance for TB Drug Development/Novartis

Drug Profile

Pretomanid - Global Alliance for TB Drug Development/Novartis

Alternative Names: Pa; PA 824

Latest Information Update: 12 Apr 2023

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At a glance

  • Originator Novartis
  • Developer Global Alliance for TB Drug Development; Viatris Inc
  • Class 2 ring heterocyclic compounds; Antituberculars; Nitroimidazoles; Oxazines; Phenyl ethers; Small molecules
  • Mechanism of Action Cell wall inhibitors; Nitric oxide stimulants; Protein synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Tuberculosis
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Tuberculosis

Most Recent Events

  • 19 Feb 2023 Efficacy and adverse events data from a phase III trial for Tuberculosis presented at the 30th Conference on Retroviruses and Opportunistic Infections 2023 (CROI-2023)
  • 19 Feb 2023 Efficacy and adverse event from a phase II/III trial in Tuberculosis presented at the 30th Conference on Retroviruses and Opportunistic Infections (CROI-2023)
  • 29 Nov 2022 Phase-II/III development in Tuberculosis (Combination Therapy, In adolescents, In the elderly, Treatment-resistant, In adults) is ongoing in Belarus (PO) (NCT02589782)
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