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G 4460

Drug Profile

G 4460

Alternative Names: c-myb antisense oligonucleotide G4460; G4460; INX 3001; INXC 3001; LR3001

Latest Information Update: 09 Mar 2015

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At a glance

  • Originator Temple University
  • Developer Genta (CEASED); University of Pennsylvania
  • Class Antineoplastics; Antisense oligonucleotides
  • Mechanism of Action Proto oncogene proteins c myb inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Chronic myeloid leukaemia; Leukaemia

Most Recent Events

  • 20 May 2008 Discontinued - Phase-I for Leukaemia in USA (IV)
  • 20 May 2008 Discontinued - Preclinical for Chronic myeloid leukaemia in USA (Parenteral)
  • 26 Oct 2006 Phase-I clinical trials in Leukaemia in USA (IV)
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