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At a glance
Originator
National Institutes of Health (USA); Neurocrine Biosciences
Developer
Medicenna Therapeutics; Neurocrine Biosciences; Sophiris Bio
Class
Antineoplastics; Immunotoxins; Interleukins; Recombinant fusion proteins
Mechanism of Action
Protein synthesis inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Yes
-
Glioma; Glioblastoma
New Molecular Entity
Yes
Highest Development Phases
Phase II
Brain metastases; Glioblastoma
Preclinical
Brain cancer
No development reported
Bladder cancer; Glioma
Discontinued
Solid tumours
Most Recent Events
29 May 2020
Updated efficacy data from a phase IIb trial in Glioblastoma presented at the 56th Annual Meeting of the American Society of Clinical Oncology (ASCO-2020)
17 Mar 2020
Medicenna plans an end-of-phase II meeting with the US FDA in the second quarter of 2020
28 Feb 2020
No recent reports of development identified for preclinical development in Glioma(In children) in USA (IV, Infusion)
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