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Recombinant human endostatin

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Drug Profile

Recombinant human endostatin

Alternative Names: Endostatin

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator Childrens Hospital Boston
  • Developer Alchemgen Therapeutics; Childrens Hospital Boston
  • Class Angiostatic proteins; Antineoplastics; Immunotherapies; Recombinant proteins
  • Mechanism of Action Angiogenesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malignant melanoma; Neuroendocrine tumours

Highest Development Phases

  • Discontinued Adenocarcinoma; Atherosclerosis; Cancer; Malignant melanoma; Neuroendocrine tumours

Most Recent Events

  • 17 Oct 2007 Preclinical trials in Cancer in Asia (SC)
  • 10 Feb 2004 EntreMed transfers all rights to endostatin to Children's Medical Center Corporation and Alchemgen Therapeutics
  • 05 May 2003 A phase I study has been added to the adverse events, pharmacokinetics, and Cancer pharmacodynamics sections

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