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Drug Profile


Alternative Names: BIMO; Bimosiamose disodium; TBC 1269; TBC 1269z

Latest Information Update: 20 Aug 2015

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At a glance

  • Originator Encysive Pharmaceuticals
  • Developer Revotar Biopharmaceuticals
  • Class Anti-inflammatories; Antiasthmatics; Glycoconjugates; Hexanes; Skin disorder therapies; Small molecules
  • Mechanism of Action E-selectin inhibitors; L-selectin inhibitors; P selectin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute lung injury
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Acute lung injury; Adult respiratory distress syndrome; Asthma; Chronic obstructive pulmonary disease; Plaque psoriasis

Most Recent Events

  • 28 Sep 2011 Final efficacy & adverse events data from a phase II trial in Chronic obstructive pulmonary disease presented at the 21st Annual Congress of the European Respiratory Society (ERS-2011)
  • 30 Mar 2011 Discontinued - Phase-I for Adult respiratory distress syndrome in Germany (Inhalation)
  • 30 Mar 2011 Discontinued - Phase-II for Plaque psoriasis in Germany (Intradermal)
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