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Uridine triphosphate

Drug Profile

Uridine triphosphate

Alternative Names: INS 316; INS 316 Diagnostic; KRN-316; Prolucin; UTP

Latest Information Update: 25 Sep 2021

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At a glance

  • Originator University of North Carolina at Chapel Hill
  • Developer Inspire Pharmaceuticals; Kirin Brewery
  • Class Diagnostic agents; Expectorants; Nucleosides; Small molecules
  • Mechanism of Action Purinoceptor P2U agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Bronchitis; Cystic fibrosis; Lung cancer; Primary ciliary dyskinesia

Most Recent Events

  • 01 Jul 2003 Inspire is analysing phase III results with the aim to decide whether to terminate or continue the programme
  • 15 Nov 2001 A study has been added to the Diagnostic Agents therapeutic trials and adverse events sections
  • 28 Jun 2001 Genentech is no longer collaborating with Inspire Pharmaceuticals on pyrimidine Y2 agonist programmes
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