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GCS 100

Drug Profile

GCS 100

Alternative Names: GBC-590; GCS-100; GCS-100LE; LJPC-101; NCCG

Latest Information Update: 02 Jan 2017

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At a glance

  • Originator Barbara Ann Karmanos Cancer Institute; Wayne State University
  • Developer GlycoGenesys; La Jolla Pharmaceutical Company; Prospect Therapeutics
  • Class Antineoplastics; Polysaccharides
  • Mechanism of Action Angiogenesis inhibitors; Apoptosis stimulants; Cell adhesion molecule inhibitors; Galectin 3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Cancer; Chronic lymphocytic leukaemia; Colorectal cancer; Diffuse large B cell lymphoma; Liver disorders; Multiple myeloma; Pancreatic cancer; Prostate cancer; Renal failure

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 01 Jun 2016 La Jolla Pharmaceutical completes the phase II GCS-100-CS-4003 extension trial for Renal failure (chronic kidney disease) in USA (NCT02155673)
  • 08 May 2015 GCS 100 is available for licensing as of 08 May 2015. www.ljpc.com
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