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Lintuzumab Bi-213

Drug Profile

Lintuzumab Bi-213

Alternative Names: Anti-CD33 monoclonal antibody M195 Bi-213; Bi213 MOAB M195; Bi213 monoclonal antibody M195; Bismab-A; Bismuth-213 HuM195; Bismuth-213 lintuzumab; Bismuth-213-labelled HuM195; HuM195-Bi-213; Lintuzumab bismuth-213; Monoclonal antibody M195 Bi-213 conjugate; Monoclonal antibody M195 bismuth-213; SMART M195 bismuth-213

Latest Information Update: 17 Jun 2013

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At a glance

  • Originator PDL BioPharma
  • Developer Actinium Pharmaceuticals
  • Class Antineoplastics; Immunoconjugates; Monoclonal antibodies; Radiopharmaceuticals
  • Mechanism of Action CD33 antigen inhibitors; Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Acute myeloid leukaemia

Most Recent Events

  • 17 Jun 2013 Discontinued - Phase-I/II for Acute myeloid leukaemia in USA (IV)
  • 13 Jun 2012 Clinical development is ongoing in USA
  • 09 Dec 2008 Adverse events and efficacy data from a phase I/II trial in Acute myeloid leukaemia presented at the 50th Annual Meeting and Exposition of the American Society of Hematology (ASH-2008)
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