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Oregovomab - OncoQuest

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Drug Profile

Oregovomab - OncoQuest

Alternative Names: Anti-CA125-monoclonal-antibody-B43-13-AltaRex; Anti-idiotype-ovarian-cancer-vaccine-AltaRex; Anti-idiotype-ovarian-cancer-vaccine-CA125; Mab B43.13; Monoclonal antibody B43.13; OvaRex; Ovarian-cancer-vaccine-AltaRex

Latest Information Update: 19 Sep 2025

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At a glance

  • Originator AltaRex
  • Developer National Cancer Centre (Singapore); National Cancer Institute (USA); OncoQuest; University of Nebraska Medical Center; Yonsei University
  • Class Antineoplastics; Cancer vaccines; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ovarian cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Phase II Pancreatic cancer

Most Recent Events

  • 30 May 2025 Efficacy, adverse event and immunogenicity data from phase II OPERA trial in Ovarian cancer presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 30 May 2025 Efficacy and adverse event data from a phase IIb trial in Ovarian cancer presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 23 Aug 2024 CanariaBio completes the enrollment in phase II trials in Peritoneal cancer (Combination therapy, Late-stage disease, Newly diagnosed, Neoadjuvant therapy) in India (IV) (NCT05605535)

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