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Doxorubicin liposomal - Insys Therapeutics

Drug Profile

Doxorubicin liposomal - Insys Therapeutics

Alternative Names: Doxorubicin - liposome encapsulated; LED; Liposomal doxorubicin - Insys Therapeutics; PNU 108112; PNU 112 ONC 0354

Latest Information Update: 21 Aug 2019

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At a glance

  • Originator Georgetown University
  • Class Anthracyclines; Antineoplastics; Antivirals; Cytostatic antibiotics; Doxorubicins; Hepatoprotectants; Small molecules
  • Mechanism of Action P-glycoprotein inhibitors; Reactive oxygen species stimulants; RNA synthesis inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Prostate cancer

Most Recent Events

  • 15 Mar 2016 Biomarkers information updated
  • 11 Jan 2008 Discontinued - Phase-III for Breast cancer in USA (unspecified route)
  • 11 Jan 2008 Discontinued - Phase-III for Prostate cancer in USA (unspecified route)
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