Aldesleukin - Novartis

Drug Profile

Aldesleukin - Novartis

Alternative Names: Chiron IL-2; IL-2; IL-2 - Chiron; interleukin-2 - Chiron; Macrolin™; Proleukin; Recombinant IL-2; Recombinant-human-interleukin-2 - Chiron; T cell growth factor

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Chiron
  • Developer Hyup Jin Corporation; Ligand Pharmaceuticals; Novartis
  • Class Antineoplastics; Interleukins; Recombinant proteins
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Immunodeficiency disorders; Malignant melanoma; Renal cell carcinoma; Acute myeloid leukaemia; Non-Hodgkin's lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Marketed Malignant melanoma; Renal cell carcinoma
  • Discontinued HIV-1 infections; Non-Hodgkin's lymphoma

Most Recent Events

  • 16 Aug 2017 Prometheus Laboratories terminates a phase II trial due to slow accrual for Malignant melanoma (Metastatic disease, Late-stage disease, Second-line or greater therapy) in USA (IV) (NCT02796352)
  • 01 Sep 2016 Prometheus Laboratories initiates a phase II trial for Malignant melanoma (Metastatic disease; Late-stage disease, Second-line or greater therapy) in USA (NCT02796352)
  • 15 Jun 2016 Prometheus Laboratories plans a phase II trial for Malignant melanoma (Metastatic disease; Late-stage disease, Second-line or greater therapy) in USA (NCT02796352)
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