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Amphotericin B liposomal - Gilead Sciences

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Drug Profile

Amphotericin B liposomal - Gilead Sciences

Alternative Names: AmBisome; SM 26000; SM-26000 Injection; SMP 26000

Latest Information Update: 10 Oct 2025

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At a glance

  • Originator Gilead Sciences
  • Developer Drugs for Neglected Diseases Initiative Foundation; Gilead Sciences; Knight Therapeutics; Sumitomo Pharma
  • Class Antifungals; Antiprotozoals; Antipyretics; Macrolides
  • Mechanism of Action Cell membrane permeability enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Cryptococcosis; Febrile neutropenia; Fever of unknown origin; Mycoses; Visceral leishmaniasis
  • Phase II Histoplasmosis
  • Discontinued Candidiasis

Most Recent Events

  • 09 Mar 2025 Efficacy data from a phase II/III trial in Cryptococcosis released by 32nd Conference on Retroviruses and Opportunistic Infections 2025 (SROI-2025)
  • 19 Oct 2022 Phase-II clinical trials in Histoplasmosis in Brazil (IV)
  • 19 Oct 2022 Efficacy and adverse events data from a phase II trial in Histoplasmosis presented at the IDWeek 2022

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