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Drug Profile


Alternative Names: Cozaar Plus; Cozaarex D; Hizaar; Hyzaar; Lorzaar Plus; Losartan potassium/hydrochlorothiazide; Losazid; MK 954H; MK-0954A; Neo Lotan Plus; Preminent

Latest Information Update: 30 Apr 2019

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At a glance

  • Originator Merck & Co
  • Developer Banyu; Merck Sharp & Dohme; Neopharmed Gentili; sigma-tau SpA
  • Class Antihypertensives; Benzothiadiazines; Biphenyl compounds; Imidazoles; Tetrazoles
  • Mechanism of Action Angiotensin type 1 receptor antagonists; Diuretics
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Hypertension

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 26 Jan 2012 Generic equivalent available in Canada for Hypertension
  • 12 Jan 2012 Merck completes enrolment in its phase III trial for Hypertension in Japan (NCT01307046)
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