Vincristine liposomal - Spectrum Pharmaceuticals

Drug Profile

Vincristine liposomal - Spectrum Pharmaceuticals

Alternative Names: Marqibo; Sphingosomal vincristine; Vincacine; Vincristine sulfate injection; Vincristine sulfate liposomes injection; VSLI

Latest Information Update: 26 May 2017

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At a glance

  • Originator Inex Pharmaceuticals Corporation
  • Developer CASI Pharmaceuticals; Hana Biosciences; Inex Pharmaceuticals Corporation; Spectrum Pharmaceuticals; Talon Therapeutics; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Vinca alkaloids
  • Mechanism of Action Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor cell lymphoblastic leukaemia-lymphoma; Malignant melanoma
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase III Non-Hodgkin's lymphoma
  • Phase I/II Cancer
  • Preclinical Multiple myeloma
  • Discontinued Colorectal cancer; Malignant melanoma; Pancreatic cancer; Small cell lung cancer

Most Recent Events

  • 26 May 2017 Phase II development for Non-Hodgkin's lymphoma (Combination therapy, Second-line therapy or greater) is ongoing in USA
  • 10 May 2017 Spectrum Pharmaceuticals initiates enrolment in a phase II trial for Non-Hodgkin's lymphoma (Combination therapy, Second-line therapy or greater) in USA (IV) (NCT02257242)
  • 14 Mar 2017 Spectrum Pharmaceutical files for patent protection with Patent Corporation Treaty for liposomal vincristine
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