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Vincristine liposomal - Acrotech Biopharma

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Drug Profile

Vincristine liposomal - Acrotech Biopharma

Alternative Names: Marqibo; Sphingosomal vincristine; Vincacine; Vincristine sulfate injection; Vincristine sulfate liposomes injection; VSLI

Latest Information Update: 14 May 2024

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At a glance

  • Originator Inex Pharmaceuticals Corporation
  • Developer Acrotech Biopharma; CASI Pharmaceuticals; Hana Biosciences; Inex Pharmaceuticals Corporation; Talon Therapeutics; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Vinca alkaloids
  • Mechanism of Action Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malignant melanoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase III Non-Hodgkin's lymphoma
  • Phase I/II Cancer
  • Discontinued Colorectal cancer; Malignant melanoma; Multiple myeloma; Pancreatic cancer; Small cell lung cancer

Most Recent Events

  • 18 Jan 2024 Spectrum Pharmaceuticals completes a phase III trial in Non-Hodgkin's lymphoma (combination therapy, first-line therapy) in elderly patients in Germany (IV) (NCT01478542)
  • 10 Mar 2023 Discontinued - Preclinical for Multiple myeloma in USA (IV)
  • 12 May 2022 Spectrum Pharmaceuticals completes a phase I trial for Non-Hodgkin's lymphoma (Combination therapy, Second-line therapy or greater) in USA (IV) (NCT02257242)

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