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Beta lapachone

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Drug Profile

Beta lapachone

Alternative Names: ARQ 501; BRN 0181499; CO-501; NSC 26326; NSC 629749; R 1668; SL 11001

Latest Information Update: 19 Jul 2023

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At a glance

  • Originator Dana-Farber Cancer Institute
  • Developer Merck & Co
  • Class Anti-inflammatories; Antifibrotics; Antineoplastics; Eye disorder therapies; Naphthoquinones; Obesity therapies; Small molecules
  • Mechanism of Action Apoptosis stimulants; E2F1 transcription factor stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Head and neck cancer; Leiomyoma; Pancreatic cancer; Solid tumours

Most Recent Events

  • 01 Apr 2022 Sumitomo Dainippon Pharma Oncology is now called Sumitomo Pharma Oncology
  • 01 Jul 2020 Boston Biomedical has merged with Tolero Pharmaceuticals to form Sumitomo Dainippon Pharma Oncology
  • 16 Jan 2020 ArQule has been acquired and merged into Merck & Co

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