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At a glance
Originator
Wyeth
Developer
Amgen; Pfizer; Takeda
Class
Anthraquinones; Antineoplastics; Small molecules
Mechanism of Action
DNA inhibitors; DNA topoisomerase inhibitors; Immunosuppressants; Type II DNA topoisomerase inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
No
New Molecular Entity
Yes
Highest Development Phases
Marketed
Acute myeloid leukaemia; Acute nonlymphocytic leukaemia; Acute promyelocytic leukaemia; Breast cancer; Cancer; Cancer pain; Leukaemia; Liver cancer; Multiple sclerosis; Non-Hodgkin's lymphoma; Ovarian cancer
Most Recent Events
29 Nov 2021
University of Washington in collaboration with AbbVie initiates enrolment in a phase I trial for acute myeloid leukaemia (Combination therapy, Second-line or greater therapy) in USA (IV) (NCT04797767)
09 Jun 2010
OSI Pharmaceuticals has been acquired by Astellas Pharma
16 Oct 2009
Wyeth has been acquired by Pfizer
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