Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Antithrombin alfa

Drug Profile

Antithrombin alfa

Alternative Names: Antithrombin III recombinant human; Antithrombin III transgenic; ATryn; Recombinant human antithrombin III; rhATIII; Transgenic antithrombin III

Latest Information Update: 04 Nov 2017

Price : $50 *
* Final gross price and currency may vary according to local VAT and billing address.
* Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. A link to download a PDF version of the drug profile will be included in your email receipt. Adis is an information provider. We do not sell or distribute the pharmaceutical compounds written about in this database.

At a glance

  • Originator GTC Biotherapeutics
  • Developer GTC Biotherapeutics; Knight Therapeutics; LEO Pharma; rEVO Biologics
  • Class Alpha globulins; Anticoagulants; Antithrombins; Antithrombotics; Recombinant proteins
  • Mechanism of Action Thrombin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Blood coagulation disorders; Antithrombin III deficiency
  • New Molecular Entity Yes
  • Available For Licensing Yes - Antithrombin III deficiency; Blood coagulation disorders

Highest Development Phases

  • Marketed Antithrombin III deficiency
  • Phase III Blood coagulation disorders; Preeclampsia
  • Discontinued Acute lung injury; Burns; Disseminated intravascular coagulation; Solid tumours

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Coagulation-disorders(In neonates) in USA (Parenteral)
  • 01 Nov 2016 rEVO Biologics completes a phase III trial in Preeclampsia in USA (IV) (NCT02059135)
  • 25 Apr 2016 Knight Therapeutics receives Notice of Deficiency from the Health Canada for antithrombin alfa in Antithrombin III deficiency
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top