Research programme: zinc finger DNA binding protein transcription factors - Sangamo Therapeutics
Alternative Names: AAV-ZFP-VEGF; Ad-ZFP-VEGF; AdV-ZFP-VEGF; ZFP TF ATV; ZFP TF therapeutics - SangamoLatest Information Update: 26 Dec 2022
At a glance
- Originator Sangamo BioSciences
- Developer Sangamo BioSciences; Sangamo Therapeutics
- Class Gene therapies; Transcription factors; Zinc finger DNA binding proteins
- Mechanism of Action Genetic transcription modulators; Nav1.8 voltage-gated sodium channel inhibitors; TrkA receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
- Available For Licensing Yes - Age-related macular degeneration; Alzheimer's disease; Cancer; Neuropathic pain; Parkinson's disease
Highest Development Phases
- Preclinical Neurological disorders
- No development reported Neuropathic pain
- Discontinued Age-related macular degeneration; Cancer
Most Recent Events
- 26 Dec 2022 Zinc finger DNA binding protein transcription factors is still in preclinical phase for neurological disorders in USA (Sangam Therapeutics website, December 2012)
- 05 Mar 2020 Preclinical development for Parkinson's disease is ongoing in USA
- 27 Feb 2020 Biogen enters into a licensing agreement with Sangamo Therapeutics for Neurological diseases