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Tonabersat

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Drug Profile

Tonabersat

Alternative Names: SB-220453; USL-260

Latest Information Update: 31 Jan 2019

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At a glance

  • Originator GlaxoSmithKline
  • Developer Proximagen
  • Class Antimigraines; Benzamides; Benzopyrans
  • Mechanism of Action Gap junction inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Epilepsy
  • Discontinued Migraine; Neuropathic pain

Most Recent Events

  • 29 Apr 2014 Phase I development of tonabersat in Epilepsy is ongoing
  • 14 Aug 2012 Proximagen has been acquired by Upsher-Smith
  • 14 Apr 2010 Proximagen exclusively sublicenses tonabersat to Upsher-Smith Laboratories for North America ,
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