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Tadalafil - Eli Lilly and Company

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Drug Profile

Tadalafil - Eli Lilly and Company

Alternative Names: Adcirca; Cialis; GF-196960; IC-351; LY 450190; Zalutia

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator GlaxoSmithKline; ICOS Corporation
  • Developer Eli Lilly and Company; Gilead Sciences; GSK; ICOS Corporation; United Therapeutics Corporation
  • Class Antihypertensives; Benzodioxoles; Carbolines; Erectile dysfunction therapies; Gastrokinetics; Heart failure therapies; Indoles; Ischaemic heart disorder therapies; Pyridones; Small molecules; Vascular disorder therapies; Vasodilators
  • Mechanism of Action Type 5 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Benign prostatic hyperplasia; Erectile dysfunction; Pulmonary arterial hypertension
  • Phase III Duchenne muscular dystrophy
  • No development reported Raynaud's disease
  • Discontinued Angina pectoris; Female sexual dysfunction; Gastroparesis; Heart failure

Most Recent Events

  • 16 Dec 2022 Committee for Medicinal Products for Human Use (CHMP) recommends positive opinion of paediatric pulmonary arterial hypertension in European union (3743358; 9377359)
  • 15 Dec 2022 Preregistration for Pulmonary arterial hypertension (In adolescents, In children) in European Union (PO) (3743358; 9377359)
  • 22 Mar 2022 Lotus Pharmaceuticals acquires Tadalafil from Eli Lilly and Company in Taiwan

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