Resiniferatoxin - Sorrento Therapeutics

Drug Profile

Resiniferatoxin - Sorrento Therapeutics

Alternative Names: MCP-101; RTX

Latest Information Update: 21 Aug 2018

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At a glance

  • Originator National Institutes of Health (USA)
  • Developer ICOS Corporation; Mt Cook Pharma; National Institutes of Health (USA); Sorrento Therapeutics
  • Class Analgesics; Non-opioid analgesics; Small molecules
  • Mechanism of Action TRPV1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cancer pain
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Cancer pain
  • Phase I Pain
  • Discontinued Interstitial cystitis; Overactive bladder; Rhinitis

Most Recent Events

  • 13 Aug 2018 Preliminary efficacy data from a phase I trial in Pain released by Sorrento Therapeutics
  • 12 Jul 2018 Phase-I clinical trials in Pain in USA (Intra-articular) (NCT03542838)
  • 24 Jun 2018 Biomarkers information updated
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